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1.
Pretty much an accurate description of the Presidency of George W. Bush.
The economy, No Child Left Behind, the Iraq war, the budget, and the tax cuts are all example of Bush's numerous fuck ups.
by Jesse January 24, 2005
 
2.
A failure, someone who really messes up.
Omg you're such a fuck up.
by FreD July 23, 2004
 
3.
1. To make a mistake; bungle something.
2. To act carelessly, foolishly, or incorrectly.
3. To cause to be intoxicated.
Fucked up fucker.
by Sam429 March 12, 2004
 
4.
An extreme disappointment, someone who continually makes foolish mistakes and doesn't learn.
"Dave was a fuckup. He was constantly ruining good situations for selfish reasons."

by LKR December 29, 2005
 
5.
A failure at everything, total loser, unable to do anything right
Barry you fuck up!
by Barry... how ironic? March 28, 2003
 
6.
1) Mess up, screw up, failure, mistake
2) Also can be used to say shut up in a more excessive way
1) You're a total fuck up
2) Shut the fuck up!
by Whale watcher April 22, 2003
 
7.
A complete elmore or screw up.
You, sir, are a complete and utter fuck up. Good day!
by James Bullwinkle September 26, 2007