look up any word, like plopping:
 
1.
an annoying person; someone who wont leave you alone; a "stalker-like" friend.
She was a total disease... she even followed me into the bathroom!
by wise_one__aka_sara May 11, 2005
 
2.
Disease, can mean talent, looks or moves, diseased can mean hip, cool, groovy, hot, perfect, lovely, pretty, awesome.
Snake: "Check out that chick's disease Shovel"
Shovel: "Woah I wouldn't mind catching some of that!"
by Holden Morrisey Caulfield May 18, 2006
 
3.
The natural, phenotypic expression of a pathogenic cellular alteration--caused by complex social, political, economic, and environmental processes.
Although the disease cancer did not begin with the industrial revolution, it is now a major component of it because one of the most profound consequences of the event was an increase in average life expectancy particularly for those of us who live in the so-called industrialized world. Cancer needs time to develop. Another consequence, of course, has been an increase in environmental toxins as a result of our economic activity. Cancer is stimulated, biochemically, by carcinogens like those found in pesticides.
by aaaranda420 October 06, 2012
 
4.
Whiners, people who scrounge off the welfare state, other socialists and commies, gormless anarchists, woolly liberals, human rights campaigners, people who play the race card, militant atheists, educated aristocrat playboys, union workers, animal rights activists, arable farming religious nuts or anyone else who contributes nothing to the furtherment of the human species.
Not all the idiots are leftists, but most of them are, which explains why they're still poor.
by Gumba Gumba July 12, 2004
 
5.
The man, the myth, the legend. Fable Fan Forever.
used comparatively: Disease > joo
by jparkinson September 03, 2004