Italian-American slang for heartburn but it can also mean mental aggravation.

The word is Italian-American slang derived from the Italian "agitare" meaning "to agitate.

Found an article about one of the stars of The Sopranos who's working on a new movie about feuding pizza parlor
owners. The title: "Agida." ...
"Eew, I've got agita" (swallows) "Give me some soda now, YUCK!"
by Esmee June 23, 2005

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