When a woman's bra isn't very supportive and doesn't separate, squeezing the boobs together, thus forming the appearance of one large boob. This usually happens with sports bras.
When a larger chested woman wears a sports bra it is tremendously restricting. It is described as -- A large lump of two breasts squeezed together by the wearing of a sports bra. The end result is that the woman's breasts no longer have the "Lift and Separate" affect. Therefore causing the appearance of "One Boob".