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Originated in the small town of Norton, MA. This is a popularly used term when referencing a high. Is used as a way to express ones mind-state after alcohol or marijuana intake.
Wow i am "smurffed" right now!

I'm about to get "smurffed" in a bit.
by Collegekidd December 28, 2010
the act of sexual congress between two smurfs
Took her in the parking lot. She smurffed me
by Speedy November 01, 2003
to be in a state of immense intoxication due to the introduction of toxins to the body.
10 pints of wifebeater and I'm completly smurffed
by the one that got away November 04, 2003