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1.
(adj.) something or someone that goes beyond crazy.
"You're such a nutso! You ate my pet bird, tweety!"
by Neha April 11, 2004
 
2.
An awesome word used to describe something that is totally nuts, crazy or insane. Origins unknown but rumours are that it was first made popular by someone named Gavin.
"Wow, that's totally nutso." (totally my word)
by UselessFacts July 20, 2010