look up any word, like sparkle pony:
 
1.
A terrible disease which makes the victim appear 30 or more years older in appearance than they actually are in numerical age. The name comes form the 1996 Robin Williams Film ``Jack``There is no known cure, although smoking at least 3-4 large marijuana joints per week has emerged as a well documented preventative measure.
My friend`s 22 year old girlfriend appears to be in her sixties due to an ungodly case of Jack disease.
by Jackdisease survivor January 04, 2011

Words related to Jack Disease

old robin williams disease giant jack stupid ugly young
 
2.
A condition popularized by Robin Williams's role in the movie _Jack_. A person with the "jack disease" is an ugly, ugly 20-something who looks like they're fifty. To be avoided at all costs.
Damn! That Swiss girl is fucking ugly; she has jack disease!
by Javier Hdz May 11, 2006