When you mix heroin and crystal meth together in a shot. West coast slang.
That goofball sent me to the moon for hours.
by dabqueen710 June 04, 2016

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A Girl who is Smart, Pretty, Intelligent and Funny!
Usually they love to hangout and play games with other people, and are just a lovable person to be around, they also make you happy when you feel down, they are really nice and smart as well!
Goof is for Short!
Dude, that Girl is such a Goof!

She is such a Goofball!
by Bubby! September 29, 2013

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When a male has syphilis that has spread to the testicular area, resulting in a gooey discharge.
Her: "Hey darlin, wanna do it tonight?"

Him: "Sorry babe, I got the goofball, and I don't wanna infect you"
by Merpiderp January 23, 2017

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Formerly and through the late 1980s anf 1990s, slang for barbiturates. Later expanded in common vernacular to include benzodiazepines (such as Xanax and Valium).

Commonly used today to describe the recreational combination and use of heroin and methamphetamine via IV injection.
When cooking up a hit of dope, "I got a couple points of shards, too; you wanna slam a goofball?"
by Fuckingspiders October 03, 2016

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The act of inserting the entirety of one's testicles into the anus of another human being or animal.
Brandon: Hey Chad! Let's give her the goofballs!

Chad: Yeah let's do that? What about the dog!?

Brandon: Yeah! He's next.

Chad: We're such classic goofballers.
by theshizz55 November 14, 2013

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slang term for methamphetamine and other oral forms of various illegal drugs
that guy Overdosed on goofballs, now he is in a coma.
by grizzlymaster March 06, 2009

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Someone who looks studpid while doing something......see goober
Kyle looks like a goof-ball on the knee board
by Nick October 09, 2003

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The Urban Dictionary T-Shirt

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The Urban Dictionary T-Shirt

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