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modification 

The action of modifying (something)
Mr.Thielen's car needed modification
modification by Maffuzuk September 11, 2016

Modification 

When you break some of your home boys shit but dont wanna have to replace it
Rycky: "Ethan you big fat fuck you broke my couch, you owe me $300"
Ethan: "Naah homie, I made a modification to it, you actually owe me"

de-modification 

1. Is when something is so bad, or so poorly done that a simple modification will not correct it, and the project needs to be redesigned altogether or scrapped.

2. Something is modified so much, it is designed anew, or seems to be a totally different design for the same purpose. The play plywood retainer wall was demodified into a concrete bag alleged retainer wall which need to be de-modified again.
Estancia Palm Springs said their poorly consturcted Retainer Wall was "Structurally Insufficient". Whereas, they claim the wall need modification, I beleive it really needs de-modification, because it is so bad that no quick fix will do.

A modern automobile is a demodification of the horse drawn carriage.

HAMP Modification 

The process by which an individual comes across a person in distress begging for assistance and, instead of offering aid to the distressed person, proceeds to defecate on their face.
Have you heard about the Obama making home affordable mortgage modification program? That shit doesn't work at all. I tried to apply, and all I got was a HAMP Modification from the fucking bank.
HAMP Modification by Elle Bee Jay September 8, 2010

Bro-modification

to alter a word for the better by using "bro" as a modifier.
Bro-nado, Bro-mance, Bro-k, Bro-pression, Bro-gram are all Bro-modifications

Don't fuck up my Bro-gram.
Bro-modification by sweetINKd00d January 13, 2009

post transcriptional modification 

After something get's transcribed, it get's modified.
Did you see how that thing changed after it was transcribed? That's post transcriptional modification for ya, baby!