It means "De Puta Madre" and it comes from the spanish. It's what someone says when he agrees on something or he likes it.
Bill: Yo we are gonna get Tacos today.
Jorge: De Puta Madre!(dpm)

Sarah: I just bought the new Adidas Shoes.
Lucy: dpm!
by FUCKEASP December 4, 2016
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Deaths Per Minute, in various games, for example BattleField2
A: How much is your DPM ?
B: It's like 2.0
A: Hahhah, loser !
by N0Obie September 22, 2005
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DPM (Dabs per minute)
It is how many Dabs you do on average per minute.
"Hey bro I was lifting and I shot for a new personal best and increased my DPM by 10% for a whole 300 DPM"
"Bro that's crazy"
by Wife Aggro August 25, 2017
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DPM - Dirty Pussy Mouth - what you get when you go down on someone not up to par on having a clean pussy
Hey, why aren't you passing that J to me?? Because man you have DPM, go take care of it and you can blaze this with us, I don't want that slu's Disease.
by JayRyder April 20, 2005
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"He's so clueless about how stupid he sounds he's a dpm"
by mia.dancer January 10, 2009
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Digital Prostate Massage

Inserting one's finger into the anus to massage the prostate gland.
She gave me a great DPM.
by Purple January 15, 2005
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