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everyone is secretly gay/lesbian. no exceptions.
Guy1: that chick is hot
Guy2:Rule 72....
Guy1:but maybe...
Guy2: don't even try to argue with Rule 72. no exceptions.
Rule 72 by ThatCrazyGuy November 24, 2010
Related Words
If it exists, there's a Peepified version of it. If there isn't, there will be.

For those who don't know, peepification is the process of editing pictures and works of art (depicting people or any being with a definable face) to make them resemble the now deceased rapper Lil Peep.
Person 1: "Hey, check out this Mona Lisa painting I found!"
Person 2: "That looks really cool, but look at the peepified version I found of it"
Maria: "WOW! Rule 72 is really awesome!"
Rule 72 by Radicalfunjoy March 26, 2022

Rule of 72 

If you don’t practice something hard in 72 hours (3 days), you will forget it
It’s Sunday. I haven’t practiced the Rubiks Cube since Wednesday. I sit down and think: How the hell do I do this thing? Then I realize I haven’t practiced in 72 hours. I think ‘Oh... Rule of 72.’
Rule of 72 by Irreduzibel November 11, 2018

72 Hour Rule 

The 72 hour rule is in reference to the amount of time you are supposed to wait to contact a girl, after you have had coitus.
The purpose of the 72 hour rule is to have the girl lose feelings after you muck her barn so you don't have to have any awkward conversations and you wont directly have to be a dick to her.
The 72 hour rule was first implemented by Jesus Christ, who waited approximately 72 hours to rise from the grave after everyone though he had been killed.

-48 hours is not near long enough as the girl you fucked might still be holding out hope.
-96 hours is too long as what you are doing becomes too obvious and she doesn't need to know what you are doing

On the first day she will still have strong feeling
On the second day she will be sad you ghosted her
On the third day she will just be pissed off

This is why we use the 72 Hour rule.
Guy1: Bro, did you fuck her last night?
Guy2: Yah I think i’m gonna text her and tell her I don't want anything serious, but thats gonna be hella awkward
Guy1: Bro, Just do what my dawg Jesus did and use the 72 Hour Rule!
Guy2: Thats great advice! Thanks!
72 Hour Rule by JewЬоу33 January 26, 2020
Twitch chat stabs you in the back whenever possible.
Streamer Dies
Twitch chat trolls
Stream gets mad
Chatter states: Rule 724
rule 724 by cooldude222222222 April 17, 2017

Rule 723 

If you can think of it, then there is an app for that!
"Dude, we should totally have a pokemon collector game for MPK folks."
"Naah, someone probably already built it. Rule 723, dude!"
Rule 723 by paroDgr8 August 8, 2014