Assumed to have been derived from the word destroyed, 'destroid' was first noticed in an engineering document, presumably a typo. It soon took the internets by storm, and claimed its rightful place as a forum colloquialism for the word destroyed.
Guy 1: 'Dude, did you see dual-framed iron cross structure? It got fucking destroid last night.'
Guy 2: 'Hells ya dawg, best believ' it.'
Guy 3: 'What the crap is an iron cross structure?'
It is said of the situation where a person has the bad luck to make contact with his testicles against an undefined surface or object, intentioned or not.
Given the nature of the word, it is more appropriate to design cases where the interaction is made with a moving object, for example, a ball.
Although it is extremely painful for the victim, it tends to be considerably funny to people who witness it.
Today in the baseball game the pitcher took a nutshot; the baseball hit him in the nuts.
Man, I just watched the funniest nutshot video ever.