It started as a typo for ‘email chain’. It has been related to the shear number of emails one may receive on in given work day.
As in, “Boy, I sure have a case of ‘Email Strain’ today.”
by Mallogic July 9, 2009
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The mild pain felt after masturbating many times in one day.

Caused by the constant tension of the Penis Muscle, could also be caused by keeping the penis in an unnatural position.
(Basically, it's just because Person A has had an erection for a long time)
*Start Call*

John: Hey fam, I met this sket Jane, wanna go shag her tonite?

John2: Nah fam, I got Cock Strain init.

John: Fuckin' Ell John2, You need to stop jackin', ya' feel me?

John2: Yeah sorry Bruv.

*End Call*
by Clownshitter November 2, 2017
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Marijuana grown by a fucking retard.
Tom and Rick keep growing that dirty sego strain.
by masterkush June 16, 2008
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1. the sounds usually heard during an intense or explosive orgasim.
2. the sounds unintentionally created while ultimatly straining a stool from the anal cavity
1. dude, i was showin her my o face! but i bet the neighbors next door heard my ultimate strain! they looked at me wierd the next day... u showed my man flower off!
2. when i was droppin that stink nugget from my brown eye, the burning sensation was so intense that it seared and scortched my anal flower; my ultimate strain was so loud it shook the walls and helped alleviated the pain from my shit stool.
by The-Clasp / ashen skies. September 24, 2003
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A strain of Marijuana derived from the ChemDog strain
Yo have you tried smoking that new chem strain that Johnny has been breeding? It's amazing!
by Mr. Martinez November 5, 2013
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Groin Strain originated Gay Video Salesman originated from Steveid originated from dave the pony orginated from David Harris ESQ
by Triptrip December 2, 2004
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Confusing. Perplexing.

Something that takes great effort to figure out.
Stated on the final episode of Firefly by a bounty hunter when asked how he managed to get into the ship.
Kaley: What--how..(trying to understand how this is possible).
Erley: Strains the mind a bit don't it?
by vordmeister1001 January 22, 2011
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