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To punch or hit someone (usually in the face) for a good or for no reason at all.
Someone who got snuffed might or would say:

"I don't know why he fucking snuffed me but he's gonna catch it"
Snuffed by SaraM1 January 14, 2008
After that fool started talking hella shit, i SNUFFED his ass and he was laide out...
Snuffed by Stylez September 16, 2003
v. To get the shit knocked outta you or someone else.
"Yo, that nigga was runnin his mouth and he snuffed"
"Yea they said that yo ass was next, so peace"
snuffed by C-Dub May 13, 2005
The act of Bustin a Niggas Skull.
Yo Nigga Bucky got Snuffed the shit out of by davon.
snuffed by Colin Burton February 26, 2008
v. To hit with immense force, most often with a punch;

This term is most often used by lower-class African Americans when two, or more, people engage in combat.
Dat nigga got skraight snuffed, cuz!

We 'bout to snuff dat nigga who dissed on you las' week!
Snuffed by Ryan Allen November 14, 2004
Yo he took my chicken so i snuffed his ass after school..
Snuffed by chivo1080 February 2, 2010