To say things deliberatly to anger someone. It comes from cockfighting where they blow smoke up a roosters ass before they put him into the ring to fight.
He's just blowing smoke up your ass, ignore him.
by Javier xavier caviar June 14, 2017
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Used to ask someone for (or to return) a favor. Deriving from weed culture for when someone lets you smoke their weed with them for free, is now often used to ask for any kind of favor.
Bro, I’m fuckin broke until I get paid next Friday. Could you smoke me up on a couple beers tonight? I’ll for sure get you back next weekend.
by Legalizeitall666 June 20, 2018
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A term used to describe the act of flooding the enemy with as much smoke as you have. The smoke comes from smoke grenades, and this term is used commonly on first person shooters.
Bill- "Yo man, there are 5 guys in that house!"

Jack- "Smoke Em Up and run in there!"
by Goofry July 3, 2009
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To develop a new solution to a problem, usually on an impromptu basis.

The expression "What have you been doing, smoking the crack pipe?" led to "You need to back away from the crack pipe" led to "Don't worry about it, we'll just smoke something up to solve that problem."
"What are we going to do about the brand new project requirement that we just received?"

"Don't worry about it, the rest of the team and I will just smoke something up tonight and have it ready for testing tomorrow."
by Eric T. Simon April 9, 2008
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The sexual interaction of blowing smoke up your partner bootyhole.
Joe: I’m tryna smoke you up this Saturday.
Tiffany:ok
by Smoke me up March 24, 2021
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A nicer way to phrase the act of dying.
If John's cancer comes back he'll probably give up smoking.
by LongSpanner January 28, 2022
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A term used to describe the action of giving and/or receiving a rimjob and a vigorous handjob at the same time. Mainly used by homosexuals
"Hey bro do you wanna Hop on Among Us tonight?"
"Nah bro I'm too tired, how about we just smoke up"
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