prophylactic, condom

term made popular by the comedy show "The State"
Dad, those things you found under my mattress were profos.
by atom January 10, 2005
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Condensed form of "pro-fucker". A pro-fucker can be anyone from a prostitute who gets paid to perform sexual acts to an amateur high school slut. A "profo" typically sleeps around and is almost always considered "easy".

"Profo" can be used when talking about a whorish girl or it can even be used to describe a guy who gets around as well.
Female Use-
Becca: "Hey Taylor, did you hear that Sue hooked up with 4 boys last night at that frat party?"
Taylor: "Four?! Damn, what a profo."

Male Use-
Becca: "I heard back in high school Eric had a new girl friend every other week."
Jeff: "Yeah, Eric used to be a huge profo."
by Aiden Thomas April 30, 2007
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a shortened version of the word "professional"
You printed it on fancy paper? That's mad profo!
That chick is such a profo dresser, so classy!
by pseudorandom December 7, 2007
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A combination of the words "Profile" and "Photo"
You look unreal in your Profo babes!! xoxo
by _Blue_ROFL_ November 4, 2011
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