PIS is an acronym for "pretty interesting shit". Please note this is an acronym because you actually pronounce it as "piss".
Marley:Hey, check out this Stephen Hawkings lecture! It's PIS!
Bob: Wow, I'm so glad I learned about wormholes! That was PIS!
by Spozzy January 7, 2011
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PIS (Noun) is an acronym for Personal Individual Style. It can be used to describe or categorize all style which is both Personal and Individual. The term can also be interpreted more broadly to refer not only to manner of dress.
"I really like your PIS today."

"She's got some mad-hot PIS."

"Her PIS is piping hot--I mean FRESH out of the urethra!"

"You call that PIS?"
by DRSTP June 8, 2007
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the phrase you say when you get raped in counter stirke by a guy with the name moon-pie
you got pied biaotch!
by ash ketchum November 10, 2003
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A trend that started at a local university, where a roomate and a gay friend, violate and anally rape a second roomate, while the third roomate is not in town.
"Hey lets rape the roomate, since he has no witnesses; it will be a wu pi pi."
by T-More November 20, 2007
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When you're super blazed and need to go to bed
by PiedFranny January 26, 2015
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Pies. A lazy good for nothing who spends all his time getting drunk and posting pointless spam on internet message boards.
I think I'll do a Pies, tonight.
by DSX June 10, 2003
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