A word one uses (commonly by furries or e-girls) when they either can't be bothered or have the mental competence to sympathise with someone with trouble in their personal life, in reply to them seeking advice or help.

For contextual reference, the word 'oof' was derived from an internet meme, featuring the sound the player's avatar makes in the PC game 'ROBLOX' when they get killed. The original name of the meme, and the name of it's ACTUAL SOUND FILE was 'uuhhh' or 'uuhhh.wav'. This meme's name slowly changed into 'oof' after it was heavily popularised and became what is known as a 'dead' or 'normie' meme due to a mishearing, therefore making the word incorrect onomatopoeia for the sound.

Usage of the word is considered by some to be cute or, God forbid me saying this: 'quirky', but is mostly seen as a sign of insensitivity or ignorance towards a person's feelings.
Jonathan: Steve, I'm having a hard time with my parents right now. Could I talk to you about it just to get it off my chest? It'll mean a lot to me, man.

Steve: oof

Jonathan: ...

Steve: ...

Jonathan: ...We gonna talk about it or...?

Steve: r.i.p bro big oof xDDDDDD
by Earl The Llama April 27, 2019
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something you say when you die in roblox.
or something you say randomly
Yeet: wow you are stupid
you: I'm sad
someone else: oof
by oh no its another one October 19, 2019
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What you say when someone roasts you hard.
Wow oof.
by OofSlooth April 7, 2018
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oof
oof
by yomumgae November 14, 2018
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When someone describes something unfortunate which happened to them and you reply "oof" as in you understand it was unfortunate.
"I gambled $500 today and lost it all!" - you
"oof" - me
by peppapig604 July 18, 2018
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The word that intellectuals always use in the Internet

The word "oof" is popular on ROBLOX™
because that's where the word "oof" was invented

The word "oof" is a word you use when you don't know what to say in a serious conversation

If you do use this word in a serious conversation then prepare to lose a lot of friends because instead of saying something serious, you "oof'd"
Normie: "My mom is dead"
Intellectual: "oof"
Normie: "fuck you"
by Friendly normeme September 29, 2018
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