origin 1960's hippy term "one hitter quitter" in reference to amazingly potent marijuana. used now for many different drugs, however in specific reference to tha chronic, this shit has to be so bomb that even an experienced toker will hack and cough for a couple minutes and then not need another hit for at least 30 to 45 minutes...
damn yo.. i can smell it in the bag baby... that shits definately some one hitta quitta.. fa sho!!!
by rico suave February 25, 2005
One drag of a drug (usually marijuana) that immediately induces intoxication because of its high potency.
That kibbles from Canada was a one hitta quitta.
by Anonymous April 17, 2003
When someone gets hit and they dont get bac up.
when u knock someone the fuck out,when someone gets the shit punched or slapped out of them.
Damn when i punched him i hurt my hand. You should have gave that nicca a one hitta quitta.
by Richard Taylor April 16, 2003
A person who commonly indulges in one night stands.
Uh-uh, if you want somethin real leave that nigga alone he's a one hitta quita
by Jacqui January 3, 2004
When two people fight and one fighter knocks the other motherfucker out in his first punch thrown
"I got that one hitta quitta"- Three 6 Mafia
"I got in that fight and had a one hitta quitta mayne"
by cosmopolo September 29, 2005