Lean is a mixed drink originating in the Southern Rap culture. It is a mixture of Promethazine and Codeine cough syrup and a soft drink such as Sprite (usually). While other soft drinks may be used, Sprite was the original.

There are some variations of Lean. For example, Promethazine and Codeine syrup is usually Purple in color. But there are other colors of syrup that work the same way. There is a golden colored syrup (hydrocodone based) and other colors as well.

Lean slows you down. It makes you feel good. It's meant to be sipped on, and it taste damn good. One of the best feelings you will ever experience. Euphoria with a hint of sedation.
Chris: Yo man want to go to a party tonight, I heard they got kegs there?

John: I can't man.

Chris: Why not?

John: I'm sipping on that lean already bro. Don't need that alcohol.

Chris: Fuck that, gimme some!
by 813indisbihh November 11, 2009
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to punch somebody in the face or beat a person up.
im bout to lean on this dude.
by Stackz3x June 16, 2008
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Ryan: Everything seems to fall apart and work like shit.
Rod: Well, Ryan, it's lean.
by Gen-tailia June 17, 2011
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cough syrup especially one that contains a narcotic such as codiene or hydrocodone
One of the most popular ones is called tussionex which contains hydrocodone which is the same drug in vicodin and lorcet
I'm sippin' syrup 'cause I love the lean
by Shaggee January 29, 2005
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dats the homie who got me
damn! nigga don't worry next time we be on the lean!
by t-$torm April 10, 2016
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After smoking a few joints and hitting a couple of bongs:

'man, I am really lean'
by goldminegutted September 12, 2012
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