Top definition
Verb: 1). the act of a male doing something unmasculine, girly or just too feminine for words (ie; cuddling after sex).

2. the transition a man goes through after his girlfriend has had his balls in her purse for more than a month (see; pussy whipped ).

3. a process in which a man loses all of his former uniquely male qualities (personality and penis alike) and becomes little more than XY chromosome and chest hair. He is now and essentially a mangina on legs.
Guy: hey, i saw Andy watching 27 Dresses and Maid of Honor...WITHOUT Julie.

Guy2: awe man...depenisification complete.

Guy: we've lost him.
by urbanr0cker May 11, 2008
Get the mug
Get a depenisification mug for your dad Georges.