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A way of telling someone that they're fucked. When translated from Italian to English it says "cusick" a.k.a. see you sick. Usually shortened to "Cusi".
Person 1: I didn't study for my exams!

Person 2: Ha, cusimano.

Person 1: I know right.
Cusimano by n00btr00per September 29, 2011

Raquel Cathleen Cusimano

The Former moviestar standing at a low 4.11 residing in the Rancho Cucamonga area.
Raquel Cathleen Cusimano by Jewshaun November 25, 2007
An Italian family and drug dealing runs in the family. Yet are racist as hell but chills with some blacks just so they can be "safe".
The Cusmano family