Line from the movie "The Sandlot," meant to show extreme frustration towards someone's ineptitude or clueless-ness, sometimes both.
"Last night's episode of American Gladiators was wicked?"
"What's American Gladiators?"
"You're killing me, Smalls!"

"Johnson, did you back up those files like I asked"
"Umm,no, sir. I forgot"
"You're killing me, Smalls!"
by Bill so chill August 23, 2008
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Direct quote from the 1993 film "Sandlot". After being asked by Ham Porter if he wanted a s'more, Scotty Smalls replies several times with the question, "Some more what?". After his frustration grew with Scotty, Ham replies with, "You're killing me Smalls." This phrase is commonly used to express discontent or frustration towards a person.
Joe: "Hey Scott, can you pass me another Budweiser?"
Scott: "Actually dude, I just finished the last one."
Joe: "... You're killing me smalls."
by AyeMurr June 1, 2011
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A quote directly from the film "Sandlot", usually someone will say this out of sexual frustration.
Sophie: *sends a sexy picture to Cameron*
Cameron: "Ugh! You're killing me, Smalls!"
by mcfuckkkk April 7, 2017
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