The infamous invention of the ingenius Weasley twins, from the popular fantasy series Harry Potter. As its name implies, U-No-Poo causes the unfortunate victim to have certain...difficulties with his or her metabolism. I am sure that a more explicit explanation is not necessary for the time being.
"Why are you worrying about You-Know-Who? You should be worrying about U-NO-POO -- the constipation sensation that's gripping the nation!"
by Remus Lupin July 8, 2006
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people who forget how to play neon, the worst types of people
u poo
by Ashelberry August 24, 2021
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A person forgot to wipe directly on their anus leaving a U shape poo shmear.
Mickey: "Babe I want you eat your ass but there's a U of poo !"
Bottom: "oh oops I'll go shower"
by Oomph January 22, 2022
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