The gesture you give to something unpleasing to the eyes.
PV2 Solis goes those titties two thumbs down.
by PV2 Solis May 29, 2006
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Short version of a phrase made popular on the TV show "Scrubs":
"Who's got two thumbs and don't give a shit? Me, Bob Kelso!"
When someone tells you something you don't care about, you say, "Who's go two thumbs?"

If something not very important is made into a 'big deal', you can say: "Who's got two thumbs?"
by dbljr December 20, 2011
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When someone puts two thumbs up someones anus along with their penis and preforms anal sex.
You better shut up or i'll give you a Two Thumbs Up Charlie Brown
by Constable Headshot January 16, 2008
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Used in situations when someone comments on something that you really don't care about.

How to use:
1. Say "what has two thumbs and doesn't give a crap"
2. Point both your thumbs at yourself
3. Say your name followed by "nice to meet you"
"Now when the dark prince finally does call you home, please promise me you'll donate your body to Science and i don't mean medical science but NASA because when those buzzcuts all but given up on trying to figure out what a black hole is and they get one look at that space where your heart is suppose to be, well by golly they are going to say 'oh yeah, thats what it is!'"
"Hey Champ, what has two thumbs and doesn't give a crap?"
Thumbs go up
"Bob Kelso, nice to meet you!"
by Madonkadonk2 May 21, 2009
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A way to express some down under love.

The way you do it, is you point both of your thumbs down, then slowly point them out and shout "TWO DOWN UNDER....THUMBS UP!"

Only Ozzy's will (most likely) get this joke.
As we we're leaving Outback Australian steakhouse, i told the waitress "I give this place Two down under...Thumbs up."

The very American waitress gave me a look, for she did not understand down under humor.
by Xx_iNsPeCtOr-sCoObY_xX December 30, 2011
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When you stick both your thumbs in someone's bum Prying and gaping it then sticking your tongue in
by Warday1780 December 11, 2022
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