1930's expression for "fuck" (vulgar) or "see" (polite). You hear this expression in old movies, or recent movies (like Get Low) which is about the 1930's.
In the old days we'd say, "When did you take up with Sallie Mae?-- after all she's a married woman." Today we would say, "When did you start seeing Sallie Mae?" Or, "When did you start fucking Sallie Mae?"
by Gabinox October 26, 2011
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Having the ability within yourself to feel visible, use your voice, and feel you belong in every room you’re in.
Me: "I don't know if I can do this, or belong here."

Also Me: "Take up space! You deserve to be here just as everyone else."
by eshatakesupspace December 11, 2020
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(v.) to arm oneself or a group to attack a force.
The militia took up arms against the invaders.
by Kung-Fu Jesus May 3, 2004
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digging deep in your self to apply more effort toward acheiving a goal
Laura was enjoying her carefree, single life but decided to "take it up a notch" and have children.
by Bill Sween March 30, 2006
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Being taken advantage of in a variety of situations. As if you're bending over, you're in a kind of vulnerable situation where people can easily shove stuff up your ass, and you're taking it with a faint smile.
If he rents this shitty apartment for as much money as their asking, he will totally be taking it up the ass.
by Jamie M. September 22, 2005
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