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A vacation for the sole purpose of having sex. This sex can be planned with someone in advance or just with a random person you meet, but the main reason you are taking this vacation is for sex. This is different from a laycation, which is a sex getaway for two (or more if you're into that). A slaycation is strictly solo. You don't bring a partner.
I'm headed to California to meet up with that one guy.

Oh yeah girl, you need a good slaycation.
by Georgetown George Brown April 25, 2017
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Traveling to another place other than your homestead to a country where you are perceived as a desirable foreigner for the sole purpose of hooking up.
My boy Clive traveled to the U.S. Because American chicks love that British accent. He was on a total slaycation.
by drok9 December 04, 2016
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the trip that one takes to relax and unwind after committing a murder, serious manslaughter, or slaying. usually over 50 miles from scene of crime.
Example 1: When Tony Soprano asphyxiated Christopher Multisanti in season 6 of 'The Sopranos,' he took a slaycation to Vegas after the funeral as the Feds investigated the death and the family mourned.

Example 2: Notorious BIG raps about "laying up in Miami with Tamika and Tammy" after he leaves gangsters "in bloodshed" in revenge for their shooting three of his men in the song "You're Nobody Til Somebody Kills You."

"Incidents like this I take trips / Lay up in Miami with Tamika and Tammy / Some Creole C-O bitches I met on tour / Push a peach Legend Coupe, gold teeth galore / Told me meet em in the future later, they'll take me shopping

buy me lavender and fuschia Gators..."

(Shopping is a common activity in slaycations)
by Slaycation Homes For Rent April 20, 2010
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A girls or womans vacation where they must do all the planning, shopping, cooking, dishes, washing and care for the kids.
My Slaycation last year was miserable. I think I got 10 minutes on the beach.
by Lisa Burbank June 06, 2018
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