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A holiday (not necessarily Thanksgiving) wherein every man/woman/child in a household contracts a viral or bacterial infection, typically gastrointestinal in nature. Everyone ends up competing for toilet time, and the house essentially becomes an infirmary. Additionally, the individual responsible for spreading the outbreak (ground zero) is reminded of his/her lameness on every subsequent holiday.
Coworker 1: So how was your holiday break?

Coworker 2: Awful!

Coworker 1: Really? Why?

Coworker 2: My in-laws stayed with us. My mother-in-law was sick, then got all of us sick. It was a pukefest and shitfest--man it sucked. Happy Sicksgiving to me.
by Schwetty Ballz December 03, 2013
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