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A girl with a heart of gold. She always cares more about others than herself (even if she doesn't show it she still does) and she will try her absolute best to help you. She has a smile that lights up a room but her laugh is something else.... She will always make you smile and never intentionally put you down. She's always up for a challenge no matter how hard and fangirls over people like crazy. If you meet one... don't let her go!
Person A - Who's that girl with the nice smile?
Person B - That's Santiana
by yodefsaremine July 11, 2017
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When a person inside a school has very erect nipples.

Briones had santiana's. LOL OMG11!!!
by Regobilly January 30, 2008
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