Running up commonly refers to accumulating a large amount of something. In terms of the song, Scott’s running up large amounts of ‘cake,’ which commonly refers to money
But “run it up” can mean mad different things. It’s like “Run those jewels,” like how M.O.P. was saying. You know. Run it up, basically. What Remy was saying in the verse. That’s why I say it was God, because I wasn’t even thinking about none of that when I was doing it. It was just like it just came together that way