A Hanna-Barbera canine cartoon saying for "Uh-oh," beginning with THE JETSONS' Astro (1962) and continuing with Scooby-Doo in the Seventies.

Astro tended to speak a kind of English except that words with beginning consonants were replaced with an "R," and "R" was inserted in front of vowels.

Scooby-Doo was less fluent, but was given "Ruh-roh" as a kind of running gag when things were going bad.

Now "Ruh-roh" is sometimes used as a jocular trope where dogs are concerned, as in a recent news story about a dog who was accidentally released by Air Canada from his cage at the San Francisco airport. Rough meaning: "I goofed" or "I'm in trouble."

Comedy replacement for "uh oh", Scooby Doo style.

Scooby Doo's comedic mispronunciation of "Uh Oh", it is also a play on potentially dire situations, usually starting with a minor event that could escalate into something huge.

expression used in place of "uh oh"
derived from the popular cartoon show, Scooby Doo

when you FUCKING NUT inside of your mom and forget that your dad is in the bed too