This popular reference refers to the specific suicide method (Purple Kool-Aid)used by the 900+ participants of the People's Temple cult in the 1970s ran by Jim Jones.

The Nussy, or the “nose pussy”, if you will, was discovered during the corona virus pandemic of 2020. People that had to be tested for Covid-19 had to have their nose swabbed right where the brain connects, which often led to people rolling back their eyes and gagging.

A nose-swab-fetish developed from this, because we, as humans, ruin everything.

As heard in the Incubus song "Purple Kool-Aid"

Refers to poisoned Kool-Aid used in cult ritual suicides.

Purple Kool Aid is the liquid that keeps Black People alive. It is the equivalent of water to White People.

Drinking the Purple Kool-Aid will cause a person to blindly follow those that gave it to them. This definition is considered to be a misinterpretation of the Purple Kool-Aid incident in 1970.

Something that will make you hyperactive, and what African Americans Drink.

as heard in the Incubus song "Purple Kool-Aid"

there are many speculations as to what purple kool-aid could be. for example it could be a concoction of LSD, tranquilizers and purple kool-aid. or it could be a street name for a hallucinagenic drug. or it could be as simple and innocent as standard purple kool-aid.