At risk. In peril.
Most often used to describe someone or something that may be cut from scope or removed from the group.

to be in a very uncertain and dangerous situation

When an ultimate beastmaster is on the verge of birthing an astonishingly massive, football sized turd, but they haven't yet found a public restroom to devastate, so they need to use all of their skill and power to avoid unleashing that beast prematurely.

When your fucking a girl (or masturbating, whichever one piques your fancy) and you get a phone call right before you cum, thereby disrupting your "flow".

smoking crystal meth, particularly pertaining to the method involving a light bulb.

rising to stardom