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Magnum Oopus 

A person's biggest screwup.
Knocking down all the shelving in the parts department was my Magnum Oopus. What a mess.
Magnum Oopus by Hmd107 December 21, 2020
Related Words
Like bill and teds bogus adventure, the average day in the life of Ryan and Sam
"dude did you hear about their Oopus day yesterday? Steve ended up in Stephanie's panties and they beat a goat at monopoly"
Oopus by Ding Chaveze August 17, 2011
It’s like oops
but instead it’s oopus
Also oopusite
The oopusite of yes is no
Oopus I didn’t know if an iguana was a fish or a meat
A way of saying "oops" but in a weirder fashion.
This is usually used in text, but can be used in person if one already knows the meaning of "oopus."
Person 1: "Hey what'cha wanna do tomorrow night."
Person 2: "You😏"
Person 2: "Oopus!"
Person 1: "uh.... nevermind, man."

Magnum Oopsus 

A screw up so big, that it'll be the only thing your legacy will be remembered for.
Elon Musk's destruction of twitter was his Magnum Oopsus
Magnum Oopsus by MrLint April 7, 2023