Nopiest 

A superlative adjective to describe insectoid creatures in a negative connotation referring to fear of the creature. It applies most often to over-sized, parasitic, vile, exotic, dangerous, pregnant (visibly swelling with eggs, egg cases, maggots, other larvae, etc.), or creepy (overall) bugs.

"So guess what happened when we were watching television...we were attacked by the nopiest tarantula ever! It spun a very thick we from the ceiling. It had already made a giant web and laid egg cases all over it in the upper corner of the room."
"How big was it?"
"I think it was six inches long in full posture."
"Definitely the nopiest to exist."
"Yeah, and I killed it."
"What happened?"
"I was bitten by it, and my wound turned lime green."
"THE NOPIEST EVER!"

Nopiest by FSRueful January 12, 2019

Nopies 

the act or state of entering a circle shaped object in the buttox.

i got nopies last night

Nopies by aylalax77 November 28, 2010

Nopies 

Plural cute way of saying nope. It's the opposite of okie dokies

"Mom can we buy a dog?"
"Nopies"

Nopies by Buffymcc November 4, 2013

NOPEST 

The opposite of ‘dopest’. Something that is either uninteresting or wrong.

Due to conspiracy theories and poor attempts to reach a younger audience; the speaker was in reality the NOPEST lecturer ever!

NOPEST by Major Thomas Randle November 18, 2018