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To catastrophically yet predictably fuck something up. Named for the New York Mets, who have for years had strong teams on paper that get dismantled by injuries, bad leadership, or any number of factors which seem unpredictable to anyone before March (and unpredictable to anyone in Queens before normally September). Commonly referenced in sports media and even among famous Mets fans, like Jerry Seinfeld and Kevin James. The Mets are so synonymous with self-flagellation that using "Metsed" as a reference is common across all sports fans, but especially those in the Bronx (who normally support the New York Yankees), and those from the other National League East markets (especially Atlanta, but to a lesser extent Washington, D.C. and Miami).

Also Metsing, the present participle form, or Jetsed, referring to the Mets' former Shea Stadium co-tenants, the NFL's New York Jets. YouTuber UrinatingTree refers to the same phenomenon as "Lolmets".
"Dude! I told Aaron to mark his exam in the calendar two weeks ago but he slept in! He does this every year."
"Yeah, he really Metsed it this time."

The 2022 New York Mets won 101 games and led the National League East for most of the year, but in a crucial division-deciding series, they got swept by the Braves and then got swept by the Phillies in the Wild Card Series. Even in their good years, they can't help Metsing it all up.
Metsed by MarlinsMan2003 October 12, 2022
Related Words

Messed up 

A bad thing, or an unusual thing. Also a really strange thing that’s not necessary.
“Kevin, can you please move your seat towards the very back?,” said Ms. Smith

“Yeah sure, can I sit in the front though since no one sits there and I can see the board better?,” said Kevin.

“No, I’d like you to sit in the back because that way you won’t be near your friends,” said Ms. Smith.

“But why would I sit in the back when I can’t see in the back anyways? Bro that’s just messed up,” said Kevin again.
Messed up by Trinity:) October 30, 2019

Messed up 

Brandon messed up, and now he's dealing with the negative consequences.
Messed up by I_win_ January 29, 2018

mersedeh 

An attractive and passionate girl. She's a great talker and really laid back. Usually happy but when unhappy she tends to be grouchy and childish. Her problem becomes everyone's problem. At times she can be very predictable and tend to be monotonous but Knows how to have fun. She is really good at almost anything. Great kisser. Very predictable. Outgoing. Down to earth. Addictive. Attractive. Loud. Loves being in long relationships. Talkative. Not one to mess with. Rare to find. Good when found
wow that mersedeh is a keeper!
mersedeh by mersedehawsomesauce December 14, 2010

messed out

Man that party was messed out!!!
messed out by usher25 February 20, 2011
Fucked in the head. No idea about anything. Just Stupid!
You are messed. (with a disgusted look)
Messed by Rich Ferrari November 29, 2003