Jacksepticeye Syndrome 

When you yell and scream over everything.

My friend got Jacksepticeye Syndrome after I beat him in a game.

Jacksepticeye Syndrome by Theft Tv May 27, 2015

jacksepticeye syndrome 

When someone, usually when gaming, yells and screams at their screen. They're normally loud but doesn't have to be to class as jacksepticeye syndrome. Not to be confused with anything about loving jacksepticeye or being a fan.

My friend got jacksepticeye syndrome when I beat him in a game.

jacksepticeye syndrome by pseudony.com/index.html January 15, 2017

Jacksepticeye Syndrome 

Watching so much Jacksepticeye that you unintentionally fall in love with him.

I got a case of the Jacksepticeye syndrome. I mean, look how cute he is! I want to fuck his brains out.

Jacksepticeye Syndrome by The British Bostonian November 15, 2016