Jacksepticeye Syndrome

When you yell and scream over everything.

My friend got Jacksepticeye Syndrome after I beat him in a game.

by Theft Tv May 27, 2015

Jacksepticeye Syndrome

Watching so much Jacksepticeye that you unintentionally fall in love with him.

I got a case of the Jacksepticeye syndrome. I mean, look how cute he is! I want to fuck his brains out.

by The British Bostonian November 15, 2016

jacksepticeye syndrome

When someone, usually when gaming, yells and screams at their screen. They're normally loud but doesn't have to be to class as jacksepticeye syndrome. Not to be confused with anything about loving jacksepticeye or being a fan.

My friend got jacksepticeye syndrome when I beat him in a game.

by pseudony.com/index.html January 15, 2017