fo' shizzle my nizzle 

"fo shizzle ma nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother"

fo' shizzle my nizzle by Anonymous November 10, 2002

Fo' Shizzle My Nizzle 

An abbreviation of the Latin phrase, "For Shegro, My Negro."

Although modern linguists are unclear on the definition of the word 'Shegro', it is widely believed that it is related to the worship of the Roman Goddess Goddamnatsonehugebitchia. Certain daily activities were thought to cause the goddess to increase further in size; therefore, these activities were conducted 'for shegro.'

"Yo, you wanna go to the liquor store for a fifth of cat piss?"
"Fo' shizzle my nizzle!"

(Or, from the ancient Latin)

"Come hither, O Dumbassitus Putridus! Let us away to the market of bottled lusciousness!"
"For shegro, my negro!"

Fo' Shizzle My Nizzle by Hellzapoppin' September 7, 2015

fo' shizzle my nizzle 

Meaning:
1. affirmative; For sure, ma nigga

not necessarily in any racial context.
From a branch of urban (American) slang which adds 'izz' or varients of (ie izzle/izzo) to words to create a more rhyme like 'melody' to sentences.

kid 1: "It's late, I'm heading back to the hizzous... you stayin?"

kid 2: "fo' shizzle my nizzle"

fo' shizzle my nizzle by theJudge August 9, 2003

fo' shizzle my nizzle 

David Letterman said it best: I don't know what the fizzuck I'm talking about.

fo' shizzle my nizzle by David October 12, 2003

fo' shizzle my nizzle 

Originated in medival England in the 17th century, this phrase has changed in meaning completely, from the orignal shorthand denotation of "Alas! An advasary has come upon us! To the catupults!" to the modern definition of "Please grease up my penis."

Old: Bartholomew, the dastardly barbains are attacking! Foe Shizle mine nizle!

New: Bitch step up! Fo shizzle my nizzle!

fo' shizzle my nizzle by Darky April 9, 2003

fo' shizzle my nizzle 

THE REAL DEFINITION!!!

Snoop Dogg did NOT originate the colliquialism of adding the suffix' -izzle, -eezy, -iggedy and so forth to common everyday phrases. If you actually know your hip-hop history, this type of language originated from "Double Dutch Bus" by the Gap Band. Download it and listen. Frequent examples of such rhetoric are sprinkled across the track.

However, to the credit of Snoop Dee-Oh-Double-Gee, he took something retarded and made it sound FULLY SHICK M8!

"Dizzuble Dizzutch, the Dizzuble Dizzutch!"

fo' shizzle my nizzle by R. Soul October 24, 2003

fo' shizzle my nizzle 

A modernized and extended version of the infamous Shakespearean Hamlet line, "To be ... or not to be?"

"Fo' shizzle ... o' no' fo' shizzle? Dat be the quizzle, my south-central British nizzle."

fo' shizzle my nizzle by HootieFoo June 5, 2003