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1. An awesome person. Name could be used to describe others who are of equal awesomeness, except none exist.

2. A drink comprised of half jack daniels honey, half cherry vodka, with a splash of lime juice.
I didn't know what drink to order, so I ordered a Despina, which I thought would make me as awesome as Despina, but sadly it wasn't enough.

"I'm just fucking awesome."- actual quote from Despina herself
by Shorter Story May 24, 2013
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2
Greek name for "Lady". Commonly interchanged with the virgin mary's name.. the nameday is August 15th. Nicknames for Despina are Des, Desi, Debbie, Despinoula, Despinaki.
Despina Kats is the coolest ever, and Despina Vandi is a famous pop singer.
by Despinoula April 25, 2008
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3
Despina means "Lady" in greek but it's also as a name. Despina is a beauty with dark brown hair, gorgeous eyes and an amazing personality. She's the type of person to eat everything that catches her sight but not gain weight. She loves her friends and she's really outgoing. She is quite the attention seeking type and for that she gets scolded sometimes but other than that, she's a perfect human being.
Girl:Omg despina is so pretty! I wish I had her body! >.<
Boy: Ikr she's gorgeous!
by Dabdabz December 31, 2017
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