When you work at a restaurant in which you deliver food and the manager sends you all across town in many different directions.
Guy 1: Come on motherfucker how you gonna send me to Main st. and to Bumfuck Egypt all in one run. Man this a Bitch Run!

Manager: Man just take the motherfuckin run!
by Electric Funeral June 1, 2009
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When there is a person that you have some reason for not liking. And, you are talking to a friend and start going on about this person by saying mean things about them.
Mac: Are you going on a bitch run about Sara?
Codie: Why, yes I am. I hate her.
Mac: I can tell by all the things you say!
Codie: Damn right
by kycowgirl September 18, 2006
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Instead of the above definition, should this not be: "running like the bitch that you are", best said to a man as a derogatory insult? (but also versatile and useful in insulting a female, should you wish to).

Definition: a noun describing the act of running like a bitch, where bitch is probably better spelt biatch. Derogatory insult to a man, insinuating that he is better classified as a bitch than a proper man, or of course it could equally be an insult to a woman, since most women do not like to be called a bitch (or biatch), quite understadably.
That was such a bitch run.
by Joe19 June 24, 2007
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One of the most basic terms in ebonics, this is essential to know. The word bitch is not necessarily derogatory in this case. Usually used to coax a laugh out of one's homies.
See Jane run. Run, bitch, run (for your life)!
~Sinfest
by Matthias Drake May 21, 2006
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Originates from the interview scene with fictional character Shorty Meeks in Scary Movie.

In the era of internet memes, this is sometimes used in:

1. Video game footages, where you have no chance versus the approaching opponent or vice versa.

2. Any movie or video game scene, where a character attempts to bail (run for his life).
Shorty: I'm on T.V. Oh shit, first "Cops" now this. I'm gonna be a star, son!

Gail Hailstorm (Reporter): So how close were you to the victim?

Shorty: Oh real close. Right 'til the roofies wore and she woke up. Then she was all talkin' 'bout pressing charges so I just pulled my tongue outta her ass and left.

Gail Hailstorm (Reporter): If you could have spoken to her before she died, what would your last words to her have been?

Shorty: Run bitch run!
by BlazinItSince420AD November 24, 2015
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When somebody barrages you with whinings and bitchings of their lives (when usually they lead charmed existences) through IM, phone, in person(if they literally run), usually leaving you very sick and tired of said person and ready to bite their heads off, when they suddenly find an excuse to leave or they just leave, not allowing you to use the witty rebuttal you've had building up inside you.
Rich Bitch: Holy crap, my dad won't buy me a Porshe, he's getting me a BMW instead. FML! Why doesn't anyone love me? My boyfriend only buys me jewelry once a month! I only have an A- in all my classes! My dad lowered my allowance to 100 bucks a week! I should kill myself and... Oh snap, gotta go.

Normal Person: God damn it! I wanted to tell her how much of a bitch she is. Guess its just another Bitch and Run...
by pissedoffdude123 November 27, 2009
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When you have to run as fast as you can from someone who is going to kick your ass
1. "Hey I fucked your girlfriend yesterday." "Brb!" "What?" " Better Run Bitch!!!"
by Sorry mate July 25, 2015
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