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Someone knowledgeable and/or of importance and high standing in an area or feild.
1. Stop addressing me as "Dr. Cox" in front of your patients. When they find out my actual name, they tend to page me with questions when they realize just exactly how inept you really are. Oh, and as an added safety measure, from now on, I'll only be responding to "Doc," "Doctor," "Ceasar," or "The Big Cheese;" and noooo, I'm _not_ joking.

2. My dad can get us on the moon within the hour. He's a big cheese at NASA...
by NapalmStxToKids January 07, 2006
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Jul 28 Word of the Day
to sport a boner, fly the sail at full mass, rock hard, etc.
"I had a lot of cartoon characters that used to get me sexually aroused as a kid... The female reindeer from the Rudolph claymation series, when I was in preschool, I used to be bricked up watching that shit." -Jack Harlow
by real_philly February 11, 2020
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2
1. A BigCheese is the head of the gang in a given area defined as turf.

Louey drove his cadillac into chicago and asked .. "who is the BigCheese.

2. New zealands Best Desert combat BF exponent Big Cheese spelt I3igCheese Godlike omnipotent righteous mofo

3.A big peice of cheese usually gouda
1. al capone is the bigcheese around chicago

2.There is only 1 I3igCheese here comes bigcheese hide in the bunkers

3.just look in holland for bigcheese it's every friggin where
by I3igCheese October 19, 2006
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3
Person who works within 4 glass walls, mostly in charge of managing the mucky mucks.
I am the almighty big cheese. Get me my septor.
by gary b. February 09, 2004
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4
That one person who you keep going back to, even though it always ends up the same- bad. Much like a lab rat and the electrified cheese.
Mike, that bastard, is my big cheese.
by G October 26, 2003
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5
when someone gives you a big ass smile showing interest(sexually) in you or your physical appearance.
damn boy you see that girl, she just gave us the big cheese.
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