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A disease typically found in brunettes who should have been born blondes. Usually associated with no having no common sense and the frequent "I'm an idiot" moments.
After hearing about Amanda being dumbfounded and shocked in awe when she heard 'noise' protruding from the car speakers... only to find out if was actually the radio playing... the doctor diagnosed her with Amandaism.
by RyanKD December 05, 2006
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Something extraordinarily sarcastic and/or offensive yet extremely true.
Bob: You're drinking again?

Amanda: Fuck off, even Jesus turned water into wine. If he wasn't so douchey I'd probably like the fella....

Bob: Did you just call Jesus douchey?

Amanda: yea.

by WITard February 07, 2012
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