It means Party Unity My Ass.

"Most of the politicos who were paying attention to the P.U.M.A. movement of 2008 had then dismissed us as merely being sore-loser, tantrum-throwing Hillary supporters — scorned voters seeking revenge by not voting for Barack Obama in the general election.

Lost on such pundits was the simple proposal that no voter should feel shamed or bullied into placing blind partisan fidelity above other considerations when deciding upon a preferred general-election candidate.

P.U.M.A. was and remains the acronym, after all, for Party Unity My Ass."
I'll go PUMA and never vote for Donald Trump!
by Man_of_Steel_2013 May 4, 2016
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The male butthole or anus, used in a sexualized context.

Synonyms: boypussy, manhole, mancunt.
I saw that dude sitting in the sauna with his legs spread so wide his PUMA was winking at me.

Your ass is so hairy - how do you wipe? Your PUMA has to be filthy!
by KÅES March 2, 2020
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The most drivenand dedicatedgrassroots political organisation ever to arise in this Nation ; feared by corrupt Democrats and Republicans alike .
Those PUMAS are the ones no one was expecting !
by Tx.Tigg October 4, 2008
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The inverse cougar, this is an unattractive older woman who goes for younger men in bars. Using feminine wiles and the booze induced bad decision making to their advantage, they prey upon the younger man.
"We need to get out of here now. This place is Puma town."
by Slice of Fried Gold November 19, 2008
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a puma is a older woman who is a lesbian and dating a younger girl.
a 18yr old, dating her friends lesbian mom, would make the older woman or mom a puma.
by -Nycolle.(: January 4, 2011
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an acronym my friend and i have made up so that we dont disgust the boys in our class.
PUMA stands for "Pad Up My Ass".
girl 1: aw man, i have my period..
girl 2: oh really?
girl 1: yeah, i have a PUMA.

boy 1: wtf is PUMA?
by aleesshhaa... March 5, 2007
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