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Sugar Sugar Rune 

One of the shittiest anime I have ever seen. Naturally it's geared towards stupid girls. Catchy theme song, though. Avoid.
Oh god Sugar Sugar Rune sucks it's a good thing I'm HARDCORE PEDO and this arouses me JUST enough to watch.
Sugar Sugar Rune by Purdie June 24, 2006

blood rune 

A rune of blood. No comments/ questions! PERIOD.
YOU blood rune fagget, I'll punch you in the balls. YO!
A:dooode I found a BLOOD RUNE!
B:AWESOME! U CAN DO LIKE THE BEST STUFF WITH IT! THOUGH I WUDNT RECOMMEND MASTURBATING WIDDIT, YA HEAR THAT?

Glenn-Rune

A person with low energy.
Does that guy wanna play with us?
No, he's Glenn-Rune
Glenn-Rune by Høy Energi June 7, 2017

Fey Rune 

The best player in Inazuma eleven history.

Saved Mark from being trapped in a stone plus he kicks a$$ at football
Person 1: I can score a free kick like Ronaldo?

Person 2: But can you do it like Fey Rune?
Fey Rune by HDL69 February 20, 2022

MRG(Mystical Rune Gamers) 

MRG(Mystical Rune Gamers) is a professional Fortnite clan that is made up of mostly Ps4 players. MRG's leader is MRG_GIL and our founder MRG_NEGATIVE
I Wish I could join MRG(Mystical Rune Gamers)

Throw a rune on it 

To throw a rune on it is to put at least 20k into something
Are you going to invest in BHP?
Yes, I'll throw a rune on it
Throw a rune on it by Beejj86 June 24, 2021