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Fat Rat Motherfucker 

Fat is just rude. Rats are disgusting. So Fat Rat goes fine together, but doesn't sound right. Therefore Fat Rat motherfucker just another level of Fat Fuck...just worse
Say your boss pisses you off to the point in which the word fat or fat fuck, just doesn't settle with you. Fat Rat Motherfucker is pretty insulting, personally i don't think anyone would like to be called a rat or fat rat either, so Fat Rat Motherfucker just makes it more fun to say.
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BrookeAss MothaFucker

a combination of the brookeback mountain, an Ass and a Mother Fucker. Usually used in a situation where a person is being a dick and you ran out of words to call him. It literally means a gay fat mother fucker.
Dude man he took my cupcake.. hes such a brookeass mothafucker.

Motherfucker 

A term commonly used in jail by inmates to describe other inmates who cannot be raped, assaulted, or otherwise hurt due to the fact that they can, in one way or another, avoid or escape their advances.
That white boy is a Motherfucker, we were going to take 'em to the pit but he snitched to the guard.
Motherfucker by SQBastard May 16, 2011

Motherfucker 

An individual who partakes in sexual intercourse with female human creators.
John just knocked up another mother, what a motherfucker!
Motherfucker by the J Man February 27, 2015

motherfucking 

The word fucking, just a little more powerful. Adding some spice to the word.
Oh my fucking god, coronavirus sucks so motherfucking bad.

Mega Motherfucker 

A person with a massive 12" cock who fucks mothers.

Also an asshole of epic proportions
"Wow Sam is really a Mega motherfucker"
Also
"Oh My God Sam is a mega motherfucker, i hate him so much

howdy motherfuckers 

See: Howdy bitches; gender sensitive
Used as a greeting; as in "howdy motherfuckers"
howdy motherfuckers by Easterbunny October 30, 2008