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duff

as in to bone a chick. to get duffed out
i duffed this sweet dude last nite yeahhh!!!
by gap slammer November 7, 2006
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Duff

V. To plan a sexual encounter and back out soon after, to stand up.
He said he wanted to be with me, but then he duffed out and changed his mind.
by Laurie-Bell February 1, 2009
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DUFF

Jim: Bob you are my designated ugly fat friend (DUFF)
Bob: I'm not that fat!
by z108108 February 18, 2015
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duff

you are duff

omg Katey is such a duff in her friend group
by calumhood.com October 24, 2015
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Up the duff

An old Australian Slang term referring to an unplanned pregnancy, first used in 1941 and all the way through to around the 70s. Rarely used now a days.
Person 1: What is happening to her?
Person 2: She's up the duff.
by Shen Bapri March 23, 2023
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Duff

The shake at the bottom of a bag of drugs, including the seeds and stems in a bag of weed. Commonly used to describe the shake at the bottom of a bag of crystal meth.
Jeff: Hey, let me get a ball of that fire ice. Dan: All I have left is the duff, bro.
by jlthomas110880 November 25, 2020
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DUFF

Desiganted Ugly Fat Friend. A common acronym used in male cliques. Used to refer to the girl that the "hot chicks" bring along to distract the "Wingman" (every male clique has one, his job is to intercept the DUFF.) so the ycan have the more desirable males of the group.
"Dude, you sooooo got the DUFF tonight."
by TXwolfman817 February 24, 2009
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