by Autistic Retard December 16, 2016

A medicinal mixture of prescription cough syrup high in condine that is usually mixed with sprite, younger people use this mixture to get high.
by Slang-Definer August 12, 2018

Lean AKA Purple Drank is a drink usually represented in the HipHop music industry. It consists of Codeine cough syrup mixed with Sprite soda, Jolly Ranchers, and ice cubes. People will drink “Lean” as a substitute for alcohol, but most will drink it because it tastes amazing.
by The 1 and Only Lil Chungus March 15, 2019

Accepting the fact that being lean (<=15% body fat) is optimal for male health and attractiveness. A person who believes this is said to be lean pilled.
This belief exists to counter the narrative pushed by powerlifters and perma bulkers, which states that one should just get as big as possible and prioritize lifting numbers above everything else.
This belief exists to counter the narrative pushed by powerlifters and perma bulkers, which states that one should just get as big as possible and prioritize lifting numbers above everything else.
Friend: What happened to you? You used to be so strong and swole!
Me: I decided that feeling and looking my best is better than being able to bench 4 plates. I took the lean pill.
Me: I decided that feeling and looking my best is better than being able to bench 4 plates. I took the lean pill.
by OW_player June 12, 2024

The term "lean mass hyper-responder" was coined by software engineer David Feldman on July 3, 2017 while posting in his low-carb diet blog: "Cholesterol Code." The blog post called "Are you a Lean Mass Hyper-responder?" quickly circulated through the low-carb community.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
IN A SENTENCE: "Steve has always been a tall, skinny, beanpole of a guy. And then when he went on the carnivore diet, he was still skinny, but his cholesterol went through the roof. His doc said that overall he's pretty healthy, so he might just be a lean mass hyper-responder."
by Innocent Byproduct December 13, 2023

Lean is a popular drink that is mostly used for memes for example Talking ben makes lean and Ishowspeed makes lean
by Memiac (Youtube channel) March 18, 2022

Big Boy Barry: Yo, fresh, whats that in ur fridge?
Lil Fresh: Thats some lean
Big Boy Barry: Lemme have sum bro
Big Boy Barry: Aye thats some good leaaaaaaaaaaaaaaaaan nigga
Lil Fresh: Thats some lean
Big Boy Barry: Lemme have sum bro
Big Boy Barry: Aye thats some good leaaaaaaaaaaaaaaaaan nigga
by Kfc Family Bucket August 31, 2019
