Spice means weed/cannabis. Its origin is the movie "Dune" but applied to weed instead. Here's a quote from the movie Dune by Princess Irulan: "The most precious substance in the universe is the spice Mélange. The spice extends life. The spice expands consciousness. The spice is vital to space travel. The Spacing Guild and its navigators, who the spice has mutated over 4,000 years, use the orange spice gas, which gives them the ability to fold space".
by Kevin B Arnold August 21, 2010

"I was wit my nigga yesterday, but we went to the store and saw that bitchass lil boy. So I pull the gun out and started rocking at his ass. I don't know if he alive or not but I spiced his ass up."
by LightBoyDan May 2, 2019

by your moms a slut September 10, 2006

Nondescriptive, all-encompassing drug found in the Star Wars universe. It is believed to be a dusky red, fine-grained substance.
by Divisionbear May 8, 2009

by Niggadicks June 17, 2009

by That one dan January 2, 2009

by misshappenstanc December 18, 2017
