Also known as Trisomy 21. With 23 pairs of chromosomes, a person with Down Syndrome (i.e., a retard) has an extra 21st chromosome, causing several physical and mental defects. Usually easily recognized due to the retarded shape of their face and the clueless, happy expression on their face. These poor brain-dead sacks of sweaty garbage might be able to hold down a job as a greeter at Walmart, but this is about as high up the corporate ladder that these circus freaks typically go.
"Oh my god, did you see that dipshit window-licker trying to parallel park a shopping cart? What a down syndrome, fat fucking gay retard, fucking just dumbass stupid fucking loser. Let's kill him. I'll drown his ass, what a fucking puke piece of shit."
by Jack-the-stripper-ripper May 2, 2025
Get the Down Syndromemug. by pornstitute October 24, 2023
Get the Down To Clownmug. Bro #1: My girlfriend is being such a cunt right now.
Bro #2: You know what you need bro?
Bro #1: What?
Bro #2: A bro down.
Bro #2: You know what you need bro?
Bro #1: What?
Bro #2: A bro down.
by realoj September 17, 2017
Get the bro downmug. 1.
A: Hey man, wanna listen to Ok Computer?
B: Shit man, put on Let Down! That shit’s underrated as fuck!
2.
A: John, you’re such a let down!
B: Yeah, I know.
A: Hey man, wanna listen to Ok Computer?
B: Shit man, put on Let Down! That shit’s underrated as fuck!
2.
A: John, you’re such a let down!
B: Yeah, I know.
by anonymous September 25, 2023
Get the Let Downmug. I thought I was in love with this chick till I went down on her “chewy hang down”. After that, I was!
by Law-74 September 17, 2018
Get the Chewy hang downmug. by coco Isaac scara November 2, 2024
Get the glittering downmug. A person that is down the frizz is lame and uninformed on what is going on in the world. A person down the frizz is often looked down upon and yearns to be up the frizz.
by Boywhoisaman October 21, 2022
Get the Down the frizzmug.