A person jacked up on meth or some other type of speed that's been up for a extended period and is talking nonsense usually to themselves and usually moving like they are trying to dance but are changing their minds as to what body part to move first.
by Kris burkholder March 6, 2019

Latavius: Dude, I went to da club to see sum girls and I saw my own dang daughter!
Bernice: THOT TWIST!!!
Bernice: THOT TWIST!!!
by NoTaFaN923 June 6, 2018

Very similar to an alabama hotpocket, a pepperoni twist occurs when your girl's vagina is very loose, enough so that you can shove a pepperoni inside of her.
Arnold: Yo did you see that?
E: Yeah bro, that was the slickest pepperoni twist I've ever seen!
Arnold: No way she saw THAT coming...
E: Yeah bro, that was the slickest pepperoni twist I've ever seen!
Arnold: No way she saw THAT coming...
by Pepperoni Twisted ;) December 27, 2017

by Fuckmylifeidontwantlifeanymore June 7, 2018

by JustALilBittt September 17, 2020

Man 1: "Hey man, what took you so long? We were ready half an hour ago."
Man 2: "Sorry man, had a Plop Twist."
Man 2: "Sorry man, had a Plop Twist."
by Ramenboi April 2, 2020

by theblastmaster290 January 2, 2014
